Universitat de Girona: Recent submissions
Now showing items 201-220 of 1880
Methylome profiling of B and T cells along multiple sclerosis disease progression: a pilot study
Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune and neurodegenerative disease characterized by the infiltration of autoreactive immune cells into the central nervous system that leads to axonal damage, ...
Innovación social, pobreza y vulnerabilidad social. Los pequeños municipios de la provincia de Girona y la ciudad de Olot ante el reto de la cohesión social
The bursting of the real estate bubble in 2008 triggered a widespread socio-economic crisis that particularly affected Spanish cities and towns. It was a crisis that spread to countries all over the world, but especially ...
Gestión del conocimiento en la co-creación de material educativo con y para estudiantes con altas capacidades
The development of any process handles data. These data are generated from information that in turn generates knowledge. The ideal is that this knowledge provides the process with added value that allows it to improve, ...
L’extracte de fulla d’olivera redueix la pressió arterial de pacients amb hipertensió arterial lleugera sense malaltia vascular subclínica
Introduction: Hypertension is the common cardiovascular risk factor and affects 20 to 50% of the population. Treatment, with drugs or not, involves improving lifestyle. Olive leaf extract has traditionally been taken to ...
Variability in the health status and reproductive traits of European sardine stocks in the Mediterranean. Implications for fishery management
Small pelagic fish play an important ecological role mainly due to their contribution in transferring energy from low to higher trophic levels. Likewise, the capture of these species is in many cases an important nutritional ...
Molecular insights into mammalian sperm physiology: a comparative study of glutathione S-transferases in male reproduction
Male infertility is a global health problem affecting one in four infertile couples. This also has a negative repercussion on the animal breeding industry, where infertility has a detrimental impact on their balance sheets. ...
Anàlisi dels elements de contenció de l’endeutament a les administracions públiques locals
The work begins by carrying out an analysis of the indebtedness of the economic units, in order to assess their financial structures; the main theories developed are set out, which define the basic guidelines when referring ...
Characterization, improvement and application of plant elicitor peptides as new control tools against plant pathogens
La família de les Rosaceae comprèn espècies d’alta rellevància econòmica, com ho són les espècies de fruiters de clima temperat, ornamentals i medicinals. El seu cultiu, però, es veu limitat per la propagació de diversos ...
Medical imaging techniques for the analysis and measurement of composite materials
The purpose of this thesis is the research and development of methods, algorithms and tools for the analysis of composite materials. In order to improve their properties, one must employ specific techniques in order to ...
Three bibliometric analysis articles on the application of compositional analysis theory (CoDa) in the social science
Compositional data analysis is a recently applied methodology with great potential for expansion in multiple scientific disciplines.This doctoral thesis aims to help the dissemination and transfer of knowledge about the ...
La transversabilidad normativa de la salud como derecho
This doctoral thesis has the ambitious challenge of studying how social, labor, technological and environmental changes affect the reformulation of the right to health. It has become clear during the Covid-19 pandemic the ...
Study of two analogues of pituitary adenylate cyclase-activating polypeptide as novel therapeutic compounds for Huntington’s disease
Huntington’s disease (HD) is a neurodegenerative genetic disorder with no effective treatment characterized by motor discoordination, deficits in cognitive function (acquiring new knowledges, memory, understanding…), and ...
Novel insights into paternal factors influencing the maternal environment and embryo development
For many years, reproductive outcomes were considered as being solely determined by the genome of oocytes and sperm. Yet, in the last decades, many other female and male factors have also been found to be relevant. Focusing ...
Analysis and modeling spatiotemporal events on complex spatial regions
Spatial statistics is traditionally based on stationary models like Matérn fields. However, applying stationary models to complex spatial regions having physical barriers like islands or coastal areas can result in ...
Del censal al debitori: continuïtats i transformacions en el crèdit hipotecari català en l’etapa final de l’Antic Règim (regions de Barcelona i Girona, 1768-1840)
The objective of this report is to study causes and consequences of substituting annuity for obligation in the final period of the Ancient Regime in Catalonia (1768-1840), affording special attention to the regions of ...
Computational strategies for understanding the molecular basis of biochemical and biocatalytic processes
Enzymes are molecules that play a crucial role in many biological and chemical processes. To understand how they work and how to design enzymes with specific functions, it is important to study their molecular structure ...
Imaginación visual: nuevo paradigma en interfaces cerebro-máquina
This doctoral thesis focuses on the study of the use of visual imagery for the construction of brain-computer interfaces (BCI) non-invasive. Although the construction of brain-computer interfaces is already is a reality, ...
Estudi de l’alliberació del calci intracel·lular en cardiomiòcits derivats de iPSC de pacients amb taquicàrdia ventricular polimòrfica catecolaminèrgica (CPVT)
In a small region of the island of Gran Canaria, 11 cases of sudden cardiac death (SCD) were registered in emotional or physical stress situations in young individuals between 1994 and 2007 in four seemingly unrelated ...
Perspectiva diacrónica de la prefijación locativa intermedia del español
This research describes the evolution that the prefix inter has undergone from Latin to current Spanish, while focusing on the formation models of the derivatives generated by the prefix and on its meaning. Thus, we can ...
New approaches for the study and treatment of aggressive cancers
Although there are therapies for triple negative breast cancer (TNBC) and epidermal growth factor-mutated non-small cell lung cancer (EGFRm NSCLC), these two subtypes of cancer are very aggressive, and most patients develop ...
