Facultat de Medicina: Envíos recientes
Mostrando ítems 21-40 de 459
Estudio electroforético de enfermedades que cursan con disproteinemia
[spa] Gracias a los trabajos realizados con motivo de la presente tesis, se ha hallado un método de inmunoelectroforesis que facilita su obtención, pudiéndola convertir en método rutinario en hospitales, clínicas y ...
Estudio clínico de la fiebre tifoidea
[spa] A la hora de escoger un tema para la Memoria de doctorado pensamos en seguida en el que tenemos el honor de proponer a este Iltre. Tribunal, a saber: el estudio clínico de la fiebre tifoidea. Nos limitaremos al estudio ...
Paper dels receptors de les cèl·lules Natural Killer i dels seus lligands, estudiats mitjançant tecnologia NGS, en l’evolució de pacients amb neoplàsies mieloides
La present tesi doctoral consta d’una primera part de disseny i desenvolupament d’una nova metodologia per dur a terme la seqüenciació de gens codificants de receptors de les cèl·lules NK i dels seus respectius lligands ...
Les aguditzacions com a element crucial en el maneig no farmacològic de les bronquièctasis
INTRODUCCIÓ: Les bronquièctasis és una malaltia respiratòria crònica caracteritzada radiològicament per dilatacions irreversibles dels bronquis i clínicament per tos amb expectoració crònica, dispnea i aguditzacions de ...
Target Therapy in Rhabdomyosarcoma: Discovering new targets and apportunities
Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. RMS tumorigenesis involves the stalk of embryological myogenic processes. Classically, two main subgroups of RMS have been defined ...
Estudi sobre l'associació de l'índex de postura del peu amb el pic ponderat de pressió plantar en la fase de recolzament de la marxa
L'ús de paràmetres estàtics per a l'avaluació física del peu ha estat una constant, de la mateixa manera que també ho ha estat l'intent de relacionar aquests paràmetres amb les diferents patologies relacionades amb disfuncions ...
Análisis de los cambios de presión en el antepié mediante la aplicación de diferentes tratamientos ortopodológicos
Diversos estudios han medido las presiones plantares del antepié, la incidencia de hiperpresiones en pacientes diabéticos o los cambios producidos por el uso de determinados tipos de calzado o de soportes plantares, pero ...
Epigenetic regulation of 5-methylcytosine RNA modification in human cancer
The general aim of this thesis is to identify and characterize if there are DNA methylation patterns giving rise to cancer-related m5C RNA modification defects, potentially promoting malignant transformation and tumor ...
Development and application of xenograft models to predict the prognosis and study the treatment-driven evolution of pediatric sarcomas
Therapy development in cancer involves several consecutive steps including (1) the identification of the unmet medical need (disease or clinical question), (2) the establishment of clinically relevant resources or models ...
Connecting RAGE and cell plasticity in triple-negative breast cancer
RAGE is a transmembrane protein of the immunoglobulin family highly expressed during embryonic development but rarely expressed in adult healthy tissues. However, under cellular stress RAGE is re-expressed and mediates ...
Biomarkers and Combinatorial Drug Targets for a Personalized Therapy in Colorectal Cancer
The hypothesis of the present thesis is that the presence or absence of some chromatin factors may facilitate or impair the action of chemotherapeutic drugs in colorectal cancer (CRC). Chromatin factors have been proven ...
Sintagma i paradigma en l'esquizofàsia: un estudi psicopatolingüístic
Aquest estudi intenta analitzar l'estructura del llenguatge esquizofrènic amb els mètodes desenvolupats per la lingüística estructural i l'afasiologia. S'utilitza la dicotomia sintagma/paradigma. S'hi demostra la força de ...
Epigenetic Regulation of tRNA Biology in Cancer
Transfer RNAs (tRNAs) are essential molecules that allow the translation of the genetic code into amino acids. Extensive research during the last 50 years have revealed that, despite their apparently simple structure and ...
Genetic disruption of transfer RNA modifications in human cancer
Cancer was reported as the second leading cause of death in 2018 by the World Health Organisation. Cancer is defined as the set of diseases that proceeds in multiple phases generating a transformation lead by an accumulation ...
Dissecting genetic regulatory mechanisms in human pancreatic islets to gain insights into type 2 diabetes pathophysiology
Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by impaired blood glucose homeostasis that affects more than 415 million people worldwide and is a leading cause of mortality. The most prevalent ...
La qualitat de vida en les persones que pateixen esquizofrènia. Resultats de les escales genèriques i específiques.
El concepte de Qualitat de Vida (QV) apareix per a definir l’estat de benestar de les persones d’una societat i s’incorpora a la medicina quan, atesa la millora de l’efectivitat dels tractaments i l’expectativa de vida, ...
Carboxymethyl cellulose-based cryogels as scaffolds for pancreatic and skeletal muscle tissue engineering
Diabetes incidence highly increased in the last years. According to IDF (International Diabetes Federation), 463 million people suffered this disease in 2019. The estimations of diabetic people highly increase in the ...
Neuropilin 2 role in the regulation of disseminated tumour cells dormancy and metastasis in breast and head and neck cancer
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with more than 90% of ...
Decoding the genetic landscape of pediatric and young adult germinal center-derived B-cell non-Hodgkin lymphoma
B-cell non-Hodgkin lymphoma (B-NHL) of pediatric and young adult population is a diverse group of neoplasms predominantly composed of aggressive B-cell lymphomas from the germinal center (GC). Molecular characterization ...
Enhanced recording paradigms and advanced analyses of peripheral nerve fibers SPiike software
The aim of this work is to investigate the human nociceptive system at the peripheral level. Researchers are still debating how the pain perception arises from this very intricate network. The human perception is the most ...
