Departament de Ciències Mèdiques

La Universitat de Girona té més de 15.000 estudiants i 1.400 professors. Ofereix uns 50 estudis de grau i més de 20 màsters. S’organitza en 9 centres docents, 1 Escola de Doctorat, 6 centres adscrits. L’activitat de recerca es du a terme en 24 departaments, 12 instituts de recerca i més de 40 càtedres, a més d’un centenar de grups de recerca especialitzat. Té la seu a la ciutat de Girona i s’integra en el sistema d’universitats públiques catalanes.

També trobareu les tesis recol·lectades al repositori DUGi .


Si sou doctor o doctora de la Universitat de Girona i voleu publicar la vostra tesi a TDX, contacteu amb tdx@udg.edu. Per a més informació consulteu les preguntes més freqüents.

Recent Submissions

Unravelling the relevance of Plakophilin-2 and Olfactomedin-2 in obesity 

Lluch Balaña, Aina (Date of defense: 2024-10-22)

ENG- Obesity is a complex chronic disease linked to adipocyte dysfunction and a low-grade inflammatory condition leading to the impaired synthetic and secretory activity of hyperplastic depots of adipose tissue. As a ...

New insights in the study of the physiology of the adipose tissue 

Oliveras-Cañellas, Núria (Date of defense: 2024-10-09)

ENG- The prevalence of obesity has increased dramatically in recent years and has reached epidemic proportions. Obesity is a chronic multifactorial disease associated with an abnormal accumulation of dysfunctional adipose ...

Identificación y caracterización de nuevos biomarcadores para el diagnóstico de la miocardiopatía dilatada 

Perez-Serra, Alexandra (Date of defense: 2024-10-18)

ENG- Atherosclerotic cardiovascular diseases are efficiently treated with statins. These medications can cause unwanted muscle problems in some patients, leading them to discontinue treatment. In this context, the ...

Impact of serum ferritin and metformin on cognitive function in middle-aged subjects: modulation by the gut microbiome 

Rosell Díaz , Marisel (Date of defense: 2024-10-07)

ENG- The global obesity epidemic represents a major threat to public health worldwide. Obesity is associated with many complications that reduce quality of life and longevity. Complications associated with obesity include ...

Fenotipado de las mutaciones NRAS en cáncer colorrectal: caracterización clínico-molecular y búsqueda de nuevas terapias 

Queralt, Bernardo (Date of defense: 2024-09-30)

ENG- Metastatic colorectal cancer (mCRC) remains a major medical challenge, particularly in the search for effective treatments such as epidermal growth factor receptor (EGFR)-targeted therapies. While mutations in the ...

Fatty acids profile and DNA methylation in the placenta: prevention of cardiometabolic risk and obesity in childhood 

Gómez-Vilarrubla, Ariadna (Date of defense: 2024-07-24)

ENG- The increase in the prevalence of obesity worldwide over the past 50 years has led to obesity being considered the pandemic of the 21st century. Overweight and obesity are under scrutiny because the current pediatric ...

Study of endothelial dysfunction in chronic thromboembolic pulmonary hypertension and in COVID-19. Biomarkers and new targeted therapeutic strategies 

Poyatos Dorado, Paula (Date of defense: 2024-07-08)

The endothelium, the lining of our blood vessels, plays a crucial role in controlling functions such as blood flow, clotting and inflammation. When it does not function properly, called endothelial dysfunction, it can lead ...

Exploration into non-traditional risk factors of subclinical atherosclerosis in low-risk adults 

Iglesies-Grau, Josep (Date of defense: 2024-06-21)

Background: Atherosclerotic cardiovascular disease (ASCVD) manifests silently as subclinical atherosclerosis before a clinical event. Disparities in ASCVD risk, particularly among underrepresented ethnic and racial groups, ...

The flavonolignan silibinin in non-small cell lung cancer: molecular mechanisms and therapeutic relevance 

Verdura Martínez, Sara (Date of defense: 2024-06-07)

Non-small cell lung cancer (NSCLC) is a challenging disease to treat. Despite several decades of improved clinical progress, there is an unmet need to investigate how therapeutic resistance develops. In particular, managing ...

Polimorfismos de los genes moduladores de la respuesta inmune como predictores de recaída en los pacientes con mieloma múltiple 

Gonzalez Montes, Yolanda (Date of defense: 2024-04-12)

Multiple myeloma (MM) remains an incurable disease despite the incorporation of new therapies. The natural history of disease is of the relapse following treatments due to the re-emergence of the tumour from residual disease ...

Síndrome de l’espai gluti profund (deep gluteal syndrome). Bases anatòmiques de la seva fisiopatologia i indicacions quirúrgiques 

Servitja Tormo, Ramon (Date of defense: 2024-03-15)

Pain in the buttock region without lumbar pathology will lead us to focus the study on the region of the subgluteal space. This is defined as the deep gluteal syndrome. The deep gluteal syndrome is a condition with a very ...

Complicacions perioperatòries de l’adrenalectomia laparoscòpica. Experiència a la província de Girona 

Delisau-Puig, Olga (Date of defense: 2023-12-15)

INTRODUCTION: Adrenal masses are one of the most common tumors, being incidentally diagnosed in 5% of patients undergoing imaging tests. Until the beginning of the 1990s, all adrenal surgical treatment was performed through ...

El nivell i la variació del risc cardiovascular en la prevenció primària de la demència 

Fages Masmiquel, Ester (Date of defense: 2023-09-14)

Dementia causes progressive cognitive impairment and inability to lead an independent life. Currently, there is no curative treatment for it, and thus primary prevention is essential. Age is the main risk factor for ...

Predicción del riesgo cardiovascular en población de 75 o más años del Mediterráneo 

Guzmán Heras, Lidia Elizabeth (Date of defense: 2023-07-05)

The increase of elderly population in Spain is one of the most important challenges for their caregivers, healthcare professionals, and the society in general. The elderly population has the highest incidence rate of ...

Relació de la proteïna C-reactiva, el quocient neutròfils/limfòcits i l’adiponectina d’alt pes molecular amb paràmetres d’obesitat i de risc cardiometabòlic en nens prepuberals sans. Efecte modulador dels estils de vida 

Díaz Roldán, Ferran (Date of defense: 2023-07-03)

Childhood obesity is one of the most important public health problems and is associated with cardiometabolic risk factors (CMR). Low-grade inflammation plays a prominent role in the development of cardiometabolic alterations ...

Posible rol de las neuregulinas en la fisiología del tejido adiposo en asociación con obesidad y diabetes mellitus tipo 2 

Martínez Merchan, Cristina (Date of defense: 2023-06-28)

Different studies link the metabolic alterations of obesity with imbalances in neuregulin 4 levels. In this study we hypothesize that signaling of neuregulin isoforms (NRG) produced through ERBB receptors in human adipose ...

Methylome profiling of B and T cells along multiple sclerosis disease progression: a pilot study 

Celarain Sanz, Naiara (Date of defense: 2023-06-26)

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune and neurodegenerative disease characterized by the infiltration of autoreactive immune cells into the central nervous system that leads to axonal damage, ...

L’extracte de fulla d’olivera redueix la pressió arterial de pacients amb hipertensió arterial lleugera sense malaltia vascular subclínica 

Espín Sánchez, Rufina (Date of defense: 2023-06-16)

Introduction: Hypertension is the common cardiovascular risk factor and affects 20 to 50% of the population. Treatment, with drugs or not, involves improving lifestyle. Olive leaf extract has traditionally been taken to ...

Study of two analogues of pituitary adenylate cyclase-activating polypeptide as novel therapeutic compounds for Huntington’s disease 

Solés Tarrés, Irene (Date of defense: 2023-06-14)

Huntington’s disease (HD) is a neurodegenerative genetic disorder with no effective treatment characterized by motor discoordination, deficits in cognitive function (acquiring new knowledges, memory, understanding…), and ...

Estudi de l’alliberació del calci intracel·lular en cardiomiòcits derivats de iPSC de pacients amb taquicàrdia ventricular polimòrfica catecolaminèrgica (CPVT) 

Carreras Gorgals, David (Date of defense: 2023-05-30)

In a small region of the island of Gran Canaria, 11 cases of sudden cardiac death (SCD) were registered in emotional or physical stress situations in young individuals between 1994 and 2007 in four seemingly unrelated ...

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