Now showing items 81-100 of 124
Parra Acero, Helena (Date of defense: 2019-02-08)
Animal multicellular structure depends on three general mechanisms: cell adhesion, cell communication and cell differentiation. Some of these mechanisms were thought to be specific to animals. Genome sequencing of unicellular ...
Casas Lamesa, Anna (Date of defense: 2018-11-21)
Histone H1 is a key determinant of higher-order chromatin structures and for a long time it has been considered a main transcriptional repressor. So consistent with its biochemical properties, the absence of histone H1 was ...
Plazaola Sasieta, Haritz (Date of defense: 2018-11-29)
The chloride channel ClCN2 is expressed in glia in the mature nervous system of vertebrates and some physiological functions have been proposed. In addition, human patients with mutations in the gene or dysfunction of the ...
Bruguera Casamada, Carmina (Date of defense: 2018-11-09)
Els mètodes electroquímics s’estan estudiant com a mètodes alternatius pel tractament de l’aigua amb la finalitat d’eliminar-ne els contaminants, tant els microbiològics com els químics, en qualsevol punt del cicle de ...
Potrony Mateu, Míriam (Date of defense: 2018-09-28)
Melanoma is the malignant tumor arising from melanocytes and is the most aggressive of the common skin cancers. Melanoma is the tumor with the highest heritability (58%) and around 10% of cases occur in a familial context. ...
Castellarnau Serra, Montserrat de (Date of defense: 2018-09-20)
El virus de l’hepatitis A (HAV), el prototip del gènere Hepatovirus, té una sèrie de característiques que el diferencien de la resta de membres de la família Picornaviridae. Entre aquestes, la via de sortida descrita ...
Martí Solans, Josep (Date of defense: 2018-09-07)
El creixent nombre de genomes seqüenciats està posant de manifest que la pèrdua gènica és un fenomen recurrent que pot haver generat diversitat al llarg de la història evolutiva dels diferents grups d’organismes. En aquest ...
Pi Roig, Aina (Date of defense: 2018-04-06)
Tbx5 is a transcription factor expressed in the developing eyes, heart and upper limbs. Mutations in human TBX5 cause Holt-Oram syndrome (HOS), a condition characterised by heart and upper limb malformations. In zebrafish, ...
Cárdenas Youngs, Yexenia I. (Date of defense: 2018-06-20)
Esta tesis doctoral tuvo como objetivo principal identificar y cuantificar la presencia de bacterias patógenas, mediante el uso de indicadores de contaminación fecal y Legionella en aguas de riego aplicando métodos ...
Lema Asqui, Saúl Stalin (Date of defense: 2018-06-08)
The hypersensitive response (HR) is a paradigmatic type of programmed cell death, that occurs in response to pathogen recognition at the site of attempted invasion. Notwithstanding more than a century of research on HR, ...
Puigvert Sànchez, Marina (Date of defense: 2018-06-05)
The plant pathogen Ralstonia solanacearum is the causal agent of bacterial wilt, a highly aggressive disease responsible for important worldwide economic losses. Many virulence factors in R. solanacearum have been already ...
Tell Martí, Gemma (Date of defense: 2018-05-07)
El gen MC1R (codi OMIM: #155555) codifica pel receptor de la melanocortina 1 (MC1R) que s’expressa majoritàriament a la membrana dels melanòcits i està implicat en la regulació de la síntesi de melanina. El gen MC1R és ...
Quirós Fernández, Pablo (Date of defense: 2018-04-12)
Tanto los genes de resistencia a antibióticos (ARGs) como algunos genes de virulencia son movilizados entre las poblaciones bacterianas por elementos genéticos móviles (MGE). La transferencia horizontal de genes (HGT) está ...
Izquierdo Bouldstridge, Andrea (Date of defense: 2018-03-13)
Seven linker histone H1 variants are present in human somatic cells with distinct prevalence across cell types. Using variant-specific antibodies to H1 and hemagglutinin-tagged recombinant H1 variants expressed in breast ...
Sureda Gómez, Miquel (Date of defense: 2017-09-15)
La vía Wnt canónica es una vía de señalización muy conservada a lo largo de la evolución de los animales. Esta vía controla múltiples procesos como es la especificación del eje anteroposterior o el destino celular durante ...
Fernández Pineda, Alejandra (Date of defense: 2017-12-12)
El establecimiento de conexiones sinápticas específicas entre neuronas es esencial para la formación de los circuitos neuronales. En muchos sistemas esto requiere de una extensión hacia una capa sináptica concreta y la ...
Gholami, Behjat (Date of defense: 2017-09-18)
Osteoporosis is a general skeletal disorder. It is characterized by a low bone mass and a microarchitectural deterioration of bone tissue, which increase bone fragility and susceptibility to fracture. LRP5 is a widely ...
Ribó Gené, Sílvia (Date of defense: 2017-12-01)
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other disorders. Several ...
Olivares Castiñeira, Ivette (Date of defense: 2017-12-20)
The tracheal (respiratory) system of the Drosophila embryo is a network of interconnected epithelial tubes that supplies and exchanges the gas to maintain the homeostasis of the entire organism. Maintaining a controlled ...
Papagianni, Aikaterini (Date of defense: 2017-09-14)
During early development of bilaterian animals, specific body structures are formed and body axes are established. The establishment of body axes requires the precise and coordinated function of signalling pathways and ...