Exploring the impact of p53 activation on spatio-temporal genome topology 

    Cabrera Pasadas, Mónica (Date of defense: 2024-07-09)

    (English) The year I started this Ph.D. (2019) was the 40th anniversary of the discovery of p53 and the 30th anniversary of its characterization as a tumor suppressor. Approximately, half of all human cancers carry mutations ...

    Functional similarity between feature lists based on the joint enrichment of the gene ontology terms 

    Flores Muñoz, Pablo Javier (Date of defense: 2025-02-20)

    (English) The advent of omics technologies, such as high-throughput experiments, has revolutionized modern biology. They allow the study of the behavior of hundreds of features (such as genes, proteins, or metabolites) ...

    Genomics tools in the cloud: the new frontier in omics data analysis 

    Barcelona Cabeza, Rosa (Date of defense: 2021-10-19)

    Substantial technological advancements in next generation sequencing (NGS) have revolutionized the genomic field. Over the last years, the speed and throughput of NGS technologies have increased while their costs have ...

    Rational-design of new candidates targeting bak and bombesin receptors in cancer 

    Vila i Julià, Guillem (Date of defense: 2023-11-22)

    (English) Cancer is the second leading cause of death globally, only behind cardiovascular diseases, being a major public health issue. Cancer comprises a wide group of diseases characterized by abnormal cell growth, which ...